Ophthalmic compositions and methods for reducing oxidative damage to an eye lens

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United States of America Patent

PATENT NO 11406591
APP PUB NO 20180036232A1
SERIAL NO

15549280

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Abstract

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Methods of reducing oxidative damage to an eye of a subject are provided. Aspects of the method include intravitreal injection an antioxidant composition consisting essentially of a non-reducing sugar or a hydrate thereof. In some embodiments, the non-reducing sugar is trehalose. The methods can further include surgical removal of at least a portion of the subject's vitreous humor during a vitrectomy. Also provided are ophthalmic compositions, kits and pre-loaded injection devices for use in vitrectomy surgery which find use in the subject methods.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION INC300 EAST MARKET STREET SUITE 300 LOUISVILLE KY 40202-1959

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Braun, Ori Palo Alto, US 21 2020
O'Toole, Martin G Louisville, US 11 12
Schaal, Shlomit Louisville, US 5 5

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