USE OF IGF-1 AS PROGNOSTIC FACTOR IN CALCIFICATION OF AORTIC VALVES

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United States of America Patent

SERIAL NO

15553291

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure relates to: a composition for diagnosing aortic valve calcification diseases, comprising a preparation, which measures the protein level of inactivated IGF-1, wherein the composition is capable of diagnosing aortic valve calcification diseases involving calcification of aortic valves; a kit for diagnosing aortic valve calcification diseases, comprising the composition; a method for detecting inactivated IGF-1 so as to provide information necessary in the diagnosis of aortic valve calcification diseases; and a method for detecting inactivated IGF-1 so as to provide information necessary in the diagnosis of the progression level of aortic valve calcification diseases. According to the present disclosure, when using the composition or the kit for diagnosing aortic valve calcification diseases, it is possible to determine whether aortic valve calcification diseases, which involve the calcification of aortic valves, have occurred, and to determine the progression level of aortic valve calcification diseases which have already occurred, and thus the composition or the kit of the present disclosure can be used for more effectively diagnosing and treating aortic valve calcification diseases.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION93 DAEHAK-RO NAM-GU ULSAN 44610
THE ASAN FOUNDATION88 OLYMPIC-RO 43-GIL SONGPA-GU SEOUL 05505

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Eun Ju Seoul, KR 2 1
Song, Jae Kwan Seoul, KR 2 1

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