Highly-multiplexed fluorescent imaging

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United States of America Patent

PATENT NO 10370698
APP PUB NO 20180030504A1
SERIAL NO

15660846

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Abstract

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Provided herein is a method and system for analyzing a sample. In some embodiments the method makes use of a plurality of capture agents that are each linked to a different oligonucleotide and a corresponding plurality of labeled nucleic acid probes, wherein each of the labeled nucleic acid probes specifically hybridizes with only one of the oligonucleotides. The sample is labeled with the capture agents en masse, and sub-sets of the capture agents are detected using iterative cycles using corresponding subsets of the labeled nucleic acid probes.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYOFFICE OF THE GENERAL COUNSEL BLDG 170 3RD FL MAIN QUAD PO BOX 20386 STANFORD CA 94305-2038

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goltsev, Yury Stanford, US 22 624
Kennedy-Darling, Julia Stanford, US 13 188
Nolan, Garry P Redwood City, US 139 3143
Samusik, Nikolay Mountain View, US 32 549

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