NOVEL CHO INTEGRATION SITES AND USES THEREOF

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United States of America Patent

SERIAL NO

15783525

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Abstract

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Expression-enhancing nucleotide sequences for eukaryotic expressions systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Genomic integration sites providing enhanced expression and methods of use thereof are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.

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Patent Owner(s)

Patent OwnerAddress
REGENERON PHARMACEUTICALS INC777 OLD SAW MILL RIVER ROAD TARRYTOWN NY 10591-6707

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burakov, Darya Yonkers, US 40 191
Chen, Gang Yorktown Heights, US 944 8640
Fandl, James P LaGrangeville, US 79 1866
Shen, Ying Yorktown Heights, US 100 946

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