CD73 BLOCKADE
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United States of America Patent
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Feb 19, 2016
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Oct 10, 2014
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Abstract
This invention relates to antibodies that bind an epitope present on CD73 expressed at the surface of cells, including tumor cells, and that inhibit the enzymatic (ecto-5′ nucleotidase) activity of the CD73 enzyme. Such agents can be used for the treatment of diseases such as cancers.
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