Synthetic single domain antibody

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United States of America Patent

PATENT NO 10030068
SERIAL NO

15638509

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Abstract

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The invention relates to the identification of a highly stable single domain antibody scaffold (hs2d Ab) and its use in generating synthetic single domain antibody library (hs2d Ab-L1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT CURIE26 RUE D’ULM PARIS 75005
CNRS (CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE)75016 PARIS CEDEX 16
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS 75013
UNIVERSITE PAUL SABATIER TOULOUSE III118 ROUTE DE NARBONNE TOULOUSE 31400

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Moutel, Sandrine Paris, FR 9 12
Olichon, Aurelien Toulouse, FR 8 2
Perez, Franck Paris, FR 20 17

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