Allosteric modulators of nicotinic acetylcholine receptors
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United States of America Patent
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Mar 27, 2018
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app pub date -
Oct 9, 2017
filing date -
Mar 22, 2016
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Abstract
The present disclosure relates to compounds of formula I that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation
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