METHODS OF IDENTIFYING ESSENTIAL PROTEIN DOMAINS
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Jan 26, 2016
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Jan 26, 2015
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Provided herein, in some aspects, are methods of determining whether a candidate protein, more specifically a functional domain of a candidate protein, is essential for viability of cells of interest using clustered regularly interspaced short palindromic repeat (CPJSPR)-Cas9 technology which holds great promise for genetic screening and for the discovery of therapeutic targets.
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