Reversal binding agents for anti-factor XI/XIa antibodies and uses thereof
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United States of America Patent
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May 12, 2020
Grant Date -
Jan 25, 2018
app pub date -
May 24, 2017
filing date -
May 25, 2016
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Abstract
The present disclosure relates to reversal agents, which specifically bind to anti-Factor XI and/or anti-Factor XIa antibodies, and reverse one or more anticoagulant effects of the anti-Factor XI and/or anti-Factor XIa antibodies, as well as to methods of use thereof, such as methods for reversing anticoagulant effects of such anti-Factor XI and/or anti-Factor XIa antibodies, and to related methods for managing bleeding or bleeding risks.
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