Method for treating chronic intestinal inflammation and inflammatory bowel disease by administering antagonists of Oncostatin-M (OSM) and/or antagonists of OSM receptor-beta (OSMR)

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United States of America Patent

PATENT NO 10822406
APP PUB NO 20180022800A1
SERIAL NO

15547154

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Abstract

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The invention relates to methods of treating chronic intestinal inflammation and/or inflammatory bowel disease by administering an antagonist of oncostatin-M (OSM) and/or OSM receptor-β (OSMR). The invention also relates to methods for diagnosing or prognosing chronic intestinal inflammation and/or inflammatory bowel disease in an individual and for predicting whether or not an individual will respond to an anti-TNFα therapy. The methods comprise measuring OSM and/or OSMR in the individual.

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Patent Owner(s)

Patent OwnerAddress
OXFORD UNIVERSITY INNOVATION LIMITEDBOTLEY OXFORD OX2 0JB

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hegazy, Ahmed Nabil Oxford, GB 1 3
Owens, Benjamin Michael Joseph Oxford, GB 1 3
Powrie, Fiona Margaret Oxford, GB 2 3
West, Nathaniel Richard Oxford, GB 2 3

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