APATITE PRETREATMENT
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United States of America Patent
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Sep 29, 2017
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Jun 23, 2014
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Abstract
Apatite pretreatment methods are provided. The method is applied to the apatite solid surface prior to first chromatographic use. In one embodiment, the method may be achieved by contacting an apatite solid surface with a phosphate buffered solution at a pH of at least about 6.5 and contacting the apatite solid surface with a solution having a hydroxide.
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