Biomarkers related to kidney function and methods involving their use

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United States of America Patent

PATENT NO 10761103
APP PUB NO 20180017581A1
SERIAL NO

15541980

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a method for diagnosing in a subject Acute Kidney Injury or a related or analogous disease state. The method comprises the steps of a) providing a sample taken from the subject: b) analysing the sample from the subject to determine the level of a biomarker selected from certain atomic species; and c) comparing the level of the biomarker in the sample to a reference level of the biomarker that is characteristic of a healthy subject, eg a subject having normal renal function. An elevated level of the biomarker in the sample relative to the reference level is indicative of Acute Kidney Injury or a related or analogous disease state. The invention also relates to the use of an atomic species selected from those in Table 1 as a biomarker for Acute Kidney Injury or a related or analogous disease state, and test kits comprising an analytical element sensitive to those biomarkers.

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Patent Owner(s)

Patent OwnerAddress
NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUSTNOTTINGHAM NOTTINGHAMSHIRE NG7 2UH

International Classification(s)

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  • 2016 Application Filing Year
  • G01N Class
  • 12375 Applications Filed
  • 8515 Patents Issued To-Date
  • 68.81 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Devonald, Mark Nottingham, GB 1 0
Gardner, David Nottingham, GB 115 6293

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges463132241214274211201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7081 - 90100 +025050075010001250150017502000225025002750300032503500375040004250450047505000

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