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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
TECHNISCHE UNIVERSITAET DRESDEN	HELMHOLZSTR 10 DRESDEN 01069

International Classification(s)

• C09K:MATERIALS FOR APPLICATIONS NOT OTHERWISE PROVIDED ....
• H01L:SEMICONDUCTOR DEVICES; ELECTRIC SOLID STATE DEVICE....
• C07D:HETEROCYCLIC COMPOUNDS

• 2016 Application Filing Year
• C09K Class
• 3076 Applications Filed
• 2094 Patents Issued To-Date
• 68.08 % Issued To-Date

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Hofmann, Simone	Dresden, DE	2	4
# of filed Patents : 2 Total Citations : 4
Leo, Karl	Dresden, DE	56	673
# of filed Patents : 56 Total Citations : 673
Lygaitis, Ramunas	Dresden, DE	6	27
# of filed Patents : 6 Total Citations : 27
Oberlaender, Martin	Dresden, DE	40	853
# of filed Patents : 40 Total Citations : 853
Reineke, Sebastian	Dresden, DE	9	46
# of filed Patents : 9 Total Citations : 46
Scholz, Reinhard	Freital, DE	18	43
# of filed Patents : 18 Total Citations : 43
Zeika, Olaf	Dresden, DE	23	416
# of filed Patents : 23 Total Citations : 416

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Patent Citation Ranking

• 3 Citation Count
• C09K Class

• 32.37 % this patent is cited more than
• 7 Age

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Fee	Large entity fee	small entity fee	micro entity fee	due date
7.5 Year Payment	$3600.00	$1800.00	$900.00	Jul 18, 2025
11.5 Year Payment	$7400.00	$3700.00	$1850.00	Jul 18, 2029

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Surcharge - 7.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge - 11.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

Full Text

US Patent Application No: 2024/0254,542

SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS

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Abstract

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The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TEM3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation.

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Description

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