DOMAIN-EXCHANGED ANTIBODY

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United States of America Patent

APP PUB NO 20180016354A1
SERIAL NO

15521891

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Abstract

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The invention provides for a domain-exchanged antibody comprising a light chain (LC) composed of VL-CH3, and a heavy chain (HC) comprising VH-CH3-CH2-CH3, wherein the VL-CH3 of the LC is dimerising with the VH-CH3 of the HC thereby forming a domain-exchanged LC/HC dimer comprising a CH3LC/CH3HC domain pair, and means and method for producing the same.

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Patent Owner(s)

Patent OwnerAddress
MERCK PATENT GMBHDARMSTADT DARMSTADT HESSIAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BECKER, Stefan Darmstadt, DE 87 627
DIETRICH, Sylvia Vienna, AT 1 8
GROSS, Alec Newton, US 2 8
RÜKER, Florian Vienna, AT 9 74
WOZNIAK-KNOPP, Gordana Vienna, AT 22 218

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