FcRn antibodies and methods of use thereof
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United States of America Patent
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Jun 9, 2020
Grant Date -
Jan 18, 2018
app pub date -
Jan 29, 2016
filing date -
Jan 30, 2015
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Abstract
The present invention features antibodies that have high binding affinity to human neonatal Fc receptor (FcRn). These anti-FcRn antibodies are useful, e.g., to promote clearance of autoantibodies in a subject, to suppress antigen presentation in a subject, to block an immune response, e.g., block an immune complex-based activation of the immune response in a subject, and to treat immunological diseases (e.g., autoimmune diseases) in a subject.
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