DRUG COMPLEXES COMPRISING ALPHA-FETOPROTEIN

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United States of America Patent

SERIAL NO

15546937

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Abstract

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Compositions which comprise a hydro-phobic taxane such as paclitaxel are produced by non-covalent complexing between the taxane and alpha-fetoprotein c at a ratio of about 4 moles of taxane per mole of AFP. The complexes are water soluble and suitable for injection. Uses of the compositions for treating a subject presenting with an AFP receptor positive and taxane responsive ease cell are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY HEALTH NETWORK190 ELIZABETH STREET R FRASER ELLIOTT BUILDING - ROOM 1S-417 TORONTO M5G 2C4

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bello, Angelica M Toronto, CA 3 67
Kotra, Lakshmi P Thornhill, CA 8 81
Paige, Christopher J Toronto, CA 8 52
Sherman, Igor Toronto, CA 1 0

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