Methods for identifying, diagnosing, and predicting survival of lymphomas

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United States of America Patent

PATENT NO 10697975
APP PUB NO 20180011106A1
SERIAL NO

15630751

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Abstract

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Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICESMARYLAND 20892-7788

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Armitage, James Omaha, US 9 174
Bea, Silvia M Sabadell, ES 3 101
Campo, Guerri Elias Barcelona, ES 5 5
Chan, Wing C Pasadena, US 10 120
Connors, Joseph Vancouver, CA 3 101
Dave, Sandeep Chapel Hill, US 14 211
Delabie, Jan Toronto, CA 12 160
Fisher, Richard I Pittsford, US 6 104
Fu, Kai Omaha, US 36 154
Gascoyne, Randy North Vancouver, CA 5 105
Greiner, Timothy C Council Bluffs, US 5 111
Grogan, Thomas Tucson, US 12 182
Holte, Harald Oslo, NO 8 107
Jaffe, Elaine S Great Falls, US 8 15
Kvaloy, Stein Oslo, NO 5 98
Lister, T Andrew London, GB 3 101
Lopez-Guillermo, Armando Barcelona, ES 6 104
Miller, Thomas Tucson, US 175 3594
Montserrat, Emilio Barcelona, ES 1 2
Moreno, Victor Barcelona, ES 41 1226
Muller-Hermelink, Hans-Konrad Wurzburg, DE 7 106
Ott, German Bietigheim-Bissingen, DE 10 114
Powell, John I Ijamsville, US 3 101
Rimsza, Lisa M Scottsdale, US 7 2
Rosenwald, Andreas Wurzburg, DE 17 134
Salaverria, Itziar Barcelona, ES 3 101
Smeland, Erlend B Oslo, NO 8 15
Staudt, Louis M Bethesda, US 21 181
Tan, Bruce Chicago, US 4 116
Vose, Julie Omaha, US 3 101
Weisenburger, Dennis Glendora, US 10 114
Wilson, Wyndham Washington, US 8 140
Wright, George Rockville, US 24 1004
Zettl, Andreas Wurzburg, DE 2 99

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