THE PROTEIN KINASE ACTIVITY OF PHOSPHOGLYCERATE KINASE 1 AS A TARGET FOR CANCER TREATMENT AND DIAGNOSIS
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Jan 5, 2016
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Jan 5, 2015
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Compositions and methods for characterizing cancer cells by determining a marker of PGK1 activity. For example, methods are provided for predicting a patient response to a PGK1 inhibitor, a MEK/ERK inhibitor, an EGFR inhibitor, or a PIN1 inhibitor therapy. Methods for treating patients with such therapies are likewise provided.
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