Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions

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United States of America Patent

PATENT NO 10927417
APP PUB NO 20180010197A1
SERIAL NO

15644721

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Abstract

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Disclosed herein are assays and methods for the identification of premalignant lesions, as well as methods of determining the likelihood that such premalignant lesions will progress to lung cancer. Also disclosed are methods and assays that are useful for monitoring the progression of premalignant lesions to lung cancer. The assays and methods disclosed herein provide minimally invasive means of accurately detecting and monitoring the presence or absence of premalignant lesions, thus providing novel insights into the earliest stages of lung cancer and facilitating early detection and early intervention.

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Patent Owner(s)

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TRUSTEES OF BOSTON UNIVERSITYONE SILBER WAY BOSTON MA 02215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beane-Ebel, Jennifer E Rio Rancho, US 10 43
Lenburg, Marc E Berkeley, US 13 67
Spira, Avrum Newton, US 33 222
Tassinari, Anna Boston, US 2 8

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