Fractional initiator hybridization chain reaction

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United States of America Patent

PATENT NO 10450599
APP PUB NO 20180010166A1
SERIAL NO

15639100

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Abstract

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The present disclosure relates to methods and compositions involving HCR reactions that involve initiators that are split into two or more parts. Effective HCR is dependent upon two or more of these split initiators being brought into proximity (e.g., via binding events mediated by a target) such that a full initiator is formed that is capable of triggering HCR signal amplification.

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Patent Owner(s)

Patent OwnerAddress
CALIFORNIA INSTITUTE OF TECHNOLOGY1200 E CALIFORNIA BLVD M/C 6-32 PASADENA CA 91125

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Harry Ming Tak Pasadena, US 5 171
Pierce, Niles A Pasadena, US 38 1013

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