INHIBITION OF PRMT5 TO TREAT MTAP-DEFICIENCY-RELATED DISEASES
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Sep 9, 2015
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Sep 11, 2014
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The invention provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating patients having cancer, wherein the cancer is MTAP-deficient and/or MTA-accumulating and thus amenable to therapeutic treatment with a PRMT5 inhibitor. Kits, methods of screening for candidate PRMT5 inhibitors, and associated methods of treatment are also provided.
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