Induction of hemogenic endothelium from pluripotent stem cells by forced expression of transcription factors

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United States of America Patent

PATENT NO 10106771
APP PUB NO 20180010124A1
SERIAL NO

15684647

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Abstract

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Described herein are methods and related compositions for inducing differentiation of human pluripotent stem cells (hPSCs) into hemogenic endothelium with pan-myeloid potential or restricted potential, by forced expression in the hPSCs of a combination of transcription factors as described herein.

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Patent Owner(s)

Patent OwnerAddress
WISCONSIN ALUMNI RESEARCH FOUNDATION614 WALNUT STREET MADISON WI 53726

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Elcheva, Irina Madison, US 4 16
Slukvin, Igor Verona, US 22 38

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