METHODS AND BIOMARKERS FOR DETECTION AND TREATMENT OF LANGERHANS CELL HISTIOCYTOSIS

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United States of America Patent

SERIAL NO

15547327

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Abstract

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The present invention relates to methods and biomarkers for detection and characterization of Langerhans cell histiocytosis in biological samples (e.g., tissue samples, blood samples, plasma samples, cell samples, serum samples). In particular, the present invention provides compositions and methods for diagnosing a patient as having a Langerhans cell histiocytosis by identifying mutations in the MAP2K1 gene or gene products.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF MICHIGAN1600 HURON PARKWAY 2ND FLOOR OFFICE OF TECHNOLOGY TRANSFER ANN ARBOR MI 48109-2590

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Betz, Bryan L Ann Arbor, US 2 0
Brown, Noah A Ann Arbor, US 1 0
Elenitoba-Johnson, Kojo Ann Arbor, US 8 7
Kiel, Mark J Ann Arbor, US 10 27
Lim, Megan Ann Arbor, US 7 7
Weigelin, Helmut Ann Arbor, US 1 0

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