Multimeric death domain-containing receptor-5 (DR5) antibodies and uses thereof

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United States of America Patent

PATENT NO 10689449
APP PUB NO 20180009897A1
SERIAL NO

15544873

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Abstract

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This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.

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Patent Owner(s)

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IGM BIOSCIENCES INC325 EAST MIDDLEFIELD ROAD MOUNTAIN VIEW CA 94043

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baliga, Ramesh Redwood City, US 53 476
Keyt, Bruce Alan Hillsborough, US 21 155
Schwarzer, Max A Los Altos, US 1 25
Wang, Beatrice Tien-Yi Mountain View, US 13 160

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