Substituted imidazo[1,5-a]pyrazines as Btk inhibitors

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United States of America Patent

PATENT NO 10040805
APP PUB NO 20180009828A1
SERIAL NO

15538957

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Abstract

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The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, Formula (I) or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.

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MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gao, Xiaolei Bridgewater, US 26 134
Guiadeen, Deodial Guy Chesterfield, US 16 16
Kozlowski, Joseph A Princeton, US 108 1669
Liu, Jian Edison, US 667 5710
Liu, Shilan Shanghai, CN 22 110
Wang, Dahai Shanghai, CN 22 32

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