TETRAHYDROISOQUINOLINES AS SELECTIVE NADPH OXIDASE 2 INHIBITORS

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United States of America Patent

SERIAL NO

15708341

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Abstract

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Embodiments of bridged tetrahydroisoquinolines and methods for their use in selectively inhibiting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 are disclosed. The disclosed compounds have a structure according to general formula I or a pharmaceutically acceptable salt thereof:

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION1ST FLOOR GARDNER STEEL CONFERENCE CENTER 130 THACKERAY AVENUE PITTSBURGH PA 15260

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cifuentes-Pagano, Maria E Sewickley, US 2 0
Pagano, Patrick J Sewickley, US 5 2
Skoda, Erin M Columbia, US 9 36
Wipf, Peter Pittsburgh, US 105 492

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