Novel Forms of [R-(R*,R*)]-2-(4-Fluorophenyl)-Beta, Gamma-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)carbonyl]-1H-Pyrrole-1-Heptanoic Acid Calcium Salt (2:1)

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United States of America Patent

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15700734

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Novel forms of [R-(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptatonic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Form XXV, Form XXVI, Form XXVII, Form XXVIII, Form XXIX, and Form XXX, characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease.

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UPJOHN US 1 LLC235 EAST 42ND ST LEGAL PATENT DEPT CHIEF IP COUNSEL NEW YORK NY 10017

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Krzyzaniak, Joseph Francis Pawcatuck, US 15 63
Laurence, George Michael West Lafayette, US 5 0
Park, Aeri Lansdale, US 19 101
Quackenbush, Kevin Groton, US 5 6
Reynolds, Marie Louise Lebanon, US 5 0
Rose, Peter Robert Ledyard, US 14 16
Woods, Timothy Andrew Edinburgh, US 14 47

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