Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, HMG-CoA synthase and HMG-CoA reductase enzymatic activities

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United States of America Patent

PATENT NO 10364443
APP PUB NO 20180002727A1
SERIAL NO

15694193

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Abstract

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The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, and/or isoprenoids in microorganisms via the heterologous expression of the mvaE and mvaS genes from the organisms Listeria grayi DSM 20601, Enterococcus faecium, Enterococcus gallinarum EG2, and Enterococcus casseliflavus.

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Patent Owner(s)

Patent OwnerAddress
DANISCO US INCPALO ALTO CALIFORNIA 94304

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beck, Zachary Q Palo Alto, US 31 243
Miller, Michael C San Francisco, US 55 1151
Peres, Caroline M Palo Alto, US 31 389
Primak, Yuliya A Menlo Park, US 6 34
Pucci, Jeff P Pacifica, US 18 265
Wells, Derek H Palo Alto, US 32 383

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