Method for selecting a single cell expressing a heterogeneous combination of antibodies
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United States of America Patent
Stats
-
Jun 2, 2020
Grant Date -
Jan 4, 2018
app pub date -
Aug 21, 2017
filing date -
May 30, 2003
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention provides combinations of specific binding proteins, such as immunoglobulins, that are designed to be true combinations, essentially all components of the combination being functional and compatible with each other. The invention further provides a method for producing a composition comprising at least two different proteinaceous molecules comprising paired variable regions, the at least two proteinaceous molecules having different binding specificities, comprising paired variable regions, at least two proteinaceous molecules having different binding specificities, comprising contacting at least three different variable regions under conditions allowing for pairing of variable regions and harvesting essentially all proteinaceous molecules having binding specificities resulting from the pairing.
First Claim
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International Classification(s)
Cited Art Landscape
Patent Citation Ranking
- 5 Citation Count
- G01N Class
- 57.64 % this patent is cited more than
- 5 Age
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|---|---|---|---|---|
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