METHODS OF TREATING CEA-POSITIVE CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-CEA/ANTI-CD3 BISPECIFIC ANTIBODIES

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United States of America Patent

APP PUB NO 20180000931A1
SERIAL NO

15399122

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Abstract

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The invention provides compositions and methods for treating CEA-positive cancers. The method comprising administering a PD-1 axis binding antagonist and a bispecific antibody that targets CEA and CD3.

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Patent Owner(s)

Patent OwnerAddress
HOFFMANN-LA ROCHE INCGREAT NOTCH 150 CLOVE ROAD 8TH FLOOR LITTLE FALLS NJ 07424

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bacac, Marina Schlieren, CH 66 789
Colombetti, Sara Schlieren, CH 5 3
Klein, Christian Schlieren, CH 571 9941
Sam, Johannes Schlieren, CH 22 69
Saro, Jose Schlieren, CH 8 47
Umana, Pablo Schlieren, CH 247 5409

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