Method for treating Huntingtons's disease

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11612641
APP PUB NO 20180000907A1
SERIAL NO

15540746

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present disclosure provides methods for treating or preventing Huntington's disease (HD) in a subject in need thereof, comprising administering a therapeutic agent that activates mTORC 1 function and/or increases Ras Homolog Enriched in Striatum (Rhes) level in the subject's brain as compared to the function or level in the subject prior to treatment, and methods for modulating mHTT-associated metabolic phenotypes and/or reversal of striatal atrophy by administering a therapeutic agent that activates mTORC1 function and/or increases Ras Homolog Enriched in Striatum (Rhes) level in the subject's brain as compared to the function or level in the subject prior to treatment.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF IOWA RESEARCH FOUNDATION200 S CAPITOL STREET 2660 UNIVERSITY CAPITOL CENTRE IOWA CITY IA 52242

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Davidson, Beverly L Iowa City, US 89 1726
Lee, John H Iowa City, US 59 175

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Sep 28, 2026
7.5 Year Payment $3600.00 $1800.00 $900.00 Sep 28, 2030
11.5 Year Payment $7400.00 $3700.00 $1850.00 Sep 28, 2034
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00