NOVEL ANTI-FIBROBLAST ACTIVATION PROTEIN (FAP) ANTIBODIES AND USES DERIVED THEREOF

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United States of America Patent

SERIAL NO

15541998

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are novel human-derived antibodies specific for Fibroblast Activation Protein (FAP), preferably capable of selectively inhibiting the enzymatic activity of FAP, as well as methods related thereto. In addition, methods of diagnosing and/or monitoring diseases and treatments thereof which are associated with FAP are provided. Assays and kits related to antibodies specific for FAP are also disclosed. The novel anti-FAP antibodies can be used in pharmaceutical and diagnostic compositions for FAP-targeted immunotherapy and diagnostics.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF ZURICHRÄMISTR 71 ZURICH 8006

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BROKOPP, Chad Zurich, CH 6 8
COMBALUZIER, Benoit Urdorf, CH 7 28
GOERANSON, Mareike Wil, CH 1 2
GRIMM, Jan Dübendorf, CH 92 618
HOERSTRUP, Simon Zurich, CH 7 4
LOHMANN, Christine Zurich, CH 1 2
NITSCH, Roger Zumikon, CH 66 557

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