INHIBITORS OF HISTONE DEMETHYLASES

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United States of America Patent

SERIAL NO

15129351

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Abstract

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Compounds of the form in which Q is selected from —COOH—CH═NR12, —W, —CH2NHR13, —CH=0 and —CH(OR17)2 capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer and formulations and methods of use of such compounds.

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Patent Owner(s)

Patent OwnerAddress
GILEAD SCIENCES INC333 LAKESIDE DRIVE FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boesen, Thomas Kobenhavn, DK 24 92
Labelle, Marc Basking Ridge, US 60 719
Martyr, Cuthbert D Winnipeg, Manitoba, CA 4 1
Saraswat, Neerja Winnipeg, CA 10 175
Zhang, Rui Winnipeg, Manitoba, CA 806 5113

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