Methods of predicting clinical course and treating multiple sclerosis
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United States of America Patent
Stats
-
Aug 11, 2020
Grant Date -
Dec 21, 2017
app pub date -
Jun 19, 2017
filing date -
Mar 30, 2009
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Provided are methods and kits for classifying a subject as being more likely to have benign multiple sclerosis (BMS) or as being more likely to have typical relapsing remitting multiple sclerosis (RRMS). Classification of multiple sclerosis disease course is performed by comparing a level of expression of at least one gene involved in the RNA polymerase I pathway in a cell of the subject to a reference expression data of said at least one gene obtained from a cell of at least one subject pre-diagnosed as having BMS and/or from a cell of at least one subject pre-diagnosed as having typical RRMS, thereby classifying the subject as being more likely to have BMS or as being more likely to have typical RRMS. Also provided are methods of diagnosing and treating multiple sclerosis and methods of monitoring treatment efficiency.
First Claim
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International Classification(s)
- 2017 Application Filing Year
- C12Q Class
- 4221 Applications Filed
- 2286 Patents Issued To-Date
- 54.16 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C12Q Class
- 0 % this patent is cited more than
- 5 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Feb 11, 2028 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Feb 11, 2032 |
