Enhanced protein expression

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United States of America Patent

PATENT NO 10683528
APP PUB NO 20170362628A1
SERIAL NO

15529948

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Abstract

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The present invention relates in general to bacterial cells having genetic alterations that result in increased expression of a protein of interest and methods of making and using such cells. Aspects of the present invention include altered Gram positive microorganisms having one or more a genetic alterations that reduce the expression of a gene in the sin operon, thereby resulting in the enhanced expression of one or more proteins of interest.

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Patent Owner(s)

Patent OwnerAddress
DANISCO US INCU S A

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bongiorni, Cristina Fremont, US 18 4
Fioresi, Carol Marie Redwood City, US 4 4
Gonzales, Caguiat Rodante Santa Clara, US 1 0
Schmidt, Brian F Half Moon Bay, US 26 103
Van, Kimmenade Anita Woodside, US 26 186
Zhu, Chao Mountain View, US 70 238

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