INHIBITORS OF BRUTON'S TYROSINE KINASE

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United States of America Patent

SERIAL NO

15692261

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Abstract

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Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.

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Patent Owner(s)

Patent OwnerAddress
PHARMACYCLICS LLC995 EAST ARQUES AVENUE SUNNYVALE CA 94085

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Buggy, Joseph J Mountain View, US 104 4216
Chen, Wei Fremont, US 2011 24064
Honigberg, Lee San Francisco, US 88 9261
Loury, David J Incline Village, US 78 4230
Pan, Zhengying Austin, US 60 6283
Verner, Erik J Belmont, US 53 2388

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