USE OF POLYACETYLENIC GLYCOSIDES FOR SUPPRESSION OF GRANULOCYTIC MYELOID-DERIVED SUPPRESSOR CELL ACTIVITIES AND TUMOR METASTASIS

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United States of America Patent

SERIAL NO

15534089

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A pharmacological composition for use in inhibiting differentiation, functional activities, and population of granulo-cytic myeloid-derived suppressor cells (gMDSCs) and/or suppressing, tumor metastasis in a subject in need thereof is disclosed. The composition comprises a therapeutically effective amount of Bidens pilosa extract, or more than one polyacetylenic compounds purified or isolated from the B. pilosa extract, and a pharmaceutically acceptable carrier.

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Patent Owner(s)

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ACADEMIA SINICATAIPEI 115-29

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHEN, Yet-Ren Taipei, TW 1 0
HSIAO, Pei-Wen Taipei, TW 14 20
LIN, Sheng-Yen Taipei, TW 13 79
WEI, Wen-Chi Taipei, TW 6 6
YANG, Ning-Sun Portland, US 20 148

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