Assays for resistance to echinocandin-class drugs

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United States of America Patent

PATENT NO 10934577
APP PUB NO 20170356034A1
SERIAL NO

15601450

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Abstract

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Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.

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Patent Owner(s)

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RUTGERS THE STATE UNIVERSITY OF NEW JERSEY83 SOMERSET STREET NEW BRUNSWICK NJ 08901

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Douglas, Cameron M Piscataway, US 4 20
Kahn, Jennifer N East Brunswick, US 3 13
Kelly, Rosemarie Westfield, US 10 51
Parent, Stephen A Belle Mead, US 4 18
Park, Steven Flushing, US 33 140
Perlin, David S New York, US 16 25

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