Genetic encoding of chemical post-translational modification for phage-displayed libraries

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United States of America Patent

PATENT NO 10724034
APP PUB NO 20170355982A1
SERIAL NO

15520958

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The present application provides a method of synthesizing a genetically-encoded chemical modification of a peptide library. A vector in a substrate, such as a phage, is modified to include a peptide linker and a modification to form a genetic “barcode”. The barcode is screened against potential targets which may be used in drug discovery.

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48HOUR DISCOVERY INCROOM 4-093 11421 SASKATCHEWAN DRIVE NW EDMONTON T6G 2M9

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Derda, Ratmir Edmonton, CA 18 53
Ferrer, Vinals Daniel Edmonton, CA 1 3
Kitov, Pavel Edmonton, CA 7 96
Ng, Simon Edmonton, CA 32 554
Tjhung, Katrina Felicia Calgary, CA 3 4

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