Methods and Compositions for Selecting siRNA of Improved Functionality

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United States of America Patent

SERIAL NO

15679097

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for F12.

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Patent Owner(s)

Patent OwnerAddress
THERMO FISHER SCIENTIFIC INC81 WYMAN STREET WALTHAM MA 02451

International Classification(s)

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  • 2017 Application Filing Year
  • A61K Class
  • 21227 Applications Filed
  • 12841 Patents Issued To-Date
  • 60.50 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Khvorova, Anastasia Northborough, US 393 10160
Leake, Devin Denver, US 271 7128
Marshall, William Boulder, US 248 7212
Read, Steven Denver, US 219 4652
Reynolds, Angela Conifer, US 244 6997
Scaringe, Stephen Lafayette, US 232 6560

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  • 2 Citation Count
  • A61K Class
  • 45.09 % this patent is cited more than
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