SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND ABL AND METHODS OF USE

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United States of America Patent

SERIAL NO

15582004

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Abstract

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The present invention provides novel heteroaryl compounds of formula (I) having a pyrimidine-containing core that is linked to a 4-trifluoromethoxyphenyl group via an amine linker. Such compounds are useful for the treatment of cancers.

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Patent Owner(s)

Patent OwnerAddress
DANA-FARBER CANCER INSTITUTE450 BROOKLINE AVENUE BOSTON MA 02215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHANG, Jae Won San Diego, US 156 2497
DENG, Xianming Xiamen, CN 41 351
GRAY, Nathanael S Boston, US 247 2143
OKRAM, Barun San Marcos, US 15 154
WOJCIECHOWSKI, Amy Cheektowaga, US 7 12
ZHANG, Jianming Belmont, US 175 1287

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