Polymeric IgA-type recombinant antibody and use thereof
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United States of America Patent
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Feb 23, 2021
Grant Date -
Nov 30, 2017
app pub date -
Jul 21, 2015
filing date -
Jul 18, 2014
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Abstract
Provided are: a polymeric IgA-type recombinant antibody; a medicine containing this polymeric IgA-type recombinant antibody as an active ingredient; a method for producing this polymeric IgA type antibody, the method including the step of coexpressing an IgA-type antibody heavy-chain protein, an antibody light-chain protein, an antibody J-chain protein, and a secretory component protein within a single cell; and a method for improving the antigen-binding activity or neutralizing activity of this antibody, the method including the step of making an antibody into a polymeric IgA-type.
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