MSI-specific frameshift peptides (FSP) for prevention and treatment of cancer

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United States of America Patent

PATENT NO 10682402
APP PUB NO 20170340717A1
SERIAL NO

15663858

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Abstract

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Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said FSP. The vaccine of the present invention is particularly useful for the prevention/treatment of colorectal cancer, endometrial cancer, gastric cancer or small bowel cancer.

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Patent Owner(s)

Patent OwnerAddress
RUPRECHT-KARLS-UNIVERSITAT HEIDELBERGGRABENGASSE 1 HEIDELBERG 69117

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kloor, Matthias Ludwigshafen, DE 7 25
Reuschenbach, Miriam Heidelberg, DE 5 23
von, Knebel-Doeberitz Magnus Heidelberg, DE 11 104

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