METHOD OF REGULATING LIFESPAN USING TRANSGENIC CAENORHABDITIS ELEGANS
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United States of America Patent
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Nov 30, 2017
app pub date -
May 16, 2017
filing date -
May 24, 2016
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Abstract
The present disclosure relates to transgenic Caenorhabditis elegans including, in sensory neurons, Channelrhodopsin 2 (ChR2)::Green Fluorescence Protein (GFP) DNA in which the ChR2 gene and the GFP gene are linked, a method of producing the same, a method of regulating the lifespan thereof, and a method of screening an aging regulation candidate by using the same. The present disclosure may also provide an animal model for research into prevention/treatment of aging-related diseases by regulating the lifespan of an animal on a subject level and a method of screening a drug candidate for prevention/treatment of aging-related diseases.
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