COMBINATION THERAPY WITH GLUTAMINASE INHIBITORS

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United States of America Patent

SERIAL NO

15585523

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Abstract

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The invention relates to methods of treating cancer, myeloproliferative diseases, or immunological or neurological diseases with a combination of a glutaminase inhibitor and an anticancer agent such as an enzyme inhibitor (such as a kinase inhibitor), a mitotic inhibitor, a DNA-modifying agent, or a cytidine analog. The invention further relates to methods of treating cancer, myeloproliferative diseases, or immunological or neurological diseases that are resistant to one or more anticancer agents.

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Patent Owner(s)

Patent OwnerAddress
CALITHERA BIOSCIENCES INC343 OYSTER POINT BLVD SUITE 200 SOUTH SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
MacKinnon, Andrew L San Francisco, US 2 37
Parlati, Francesco San Francisco, US 32 551
Rodriguez, Mirna L San Jose, US 3 59
Steggerda, Susanne M San Francisco, US 10 70
Zhang, Dong San Jose, US 236 2031

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