SYSTEMS AND METHODS FOR DETERMINING THERAPEUTIC UPTAKE AND DOSING
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May 12, 2017
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May 13, 2016
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Abstract
Tools for characterizing uptake of therapeutic compounds by target tissue are disclosed along with methods for determining dosing regimen from the uptake parameters. Uptake parameters considered include partition coefficient, diffusivity, and equilibrium uptake ratio. Systems for determining partition coefficient and diffusivity in rapid uptake combinations of compounds and tissue are also reported.
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