SYSTEM AND METHOD FOR IDENTIFYING PEPTIDE SEQUENCES
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United States of America Patent
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Mar 29, 2017
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Mar 30, 2016
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A system and method for searching published genomes utilizes a robust and sensitive model to identify peptides that may serve as protein toxins. The protein toxins include unique cysteine stabilized structures and may be referred to as sequential tri-disulfide peptides (STPs) or as non-sequential tri-disulfide peptides (NTPs). While the sequence variability of STPs is so great that there are severe limitations to searching using traditional sequence-based methods, the present system and method efficiently and accurately identifies STPs as well NTPs from published genome databases, or in any peptide sequence, including artificial sequences.
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