MUSCULAR DYSTROPHY THERAPEUTIC AGENT CONTAINING PLURIPOTENT STEM CELLS DERIVED FROM DENTAL PULP

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United States of America Patent

APP PUB NO 20170327791A1
SERIAL NO

15526370

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are a therapeutic agent for muscular dystrophy employing pluripotent stem cells obtained from dental pulp and a method for preparation thereof. The therapeutic agent for muscular dystrophy comprises pluripotent stem cell-enriched human dental pulp-derived cells as the active ingredient, and is prepared by a method of preparation comprising the steps of: (a) adding dental pulp-derived cells contained in a dental pulp suspension, in a culture vessel containing feeder cells whose proliferative ability is suppressed, onto a membrane having micropores that can block feeder cells from passing therethrough and supported within the vessel in a manner that avoids direct contact of the lower side face thereof with the feeder cells, and culturing the dental pulp-derived cells on the membrane while preventing direct contact with the feeder cells, and (b) recovering the cells having grown on the membrane as the pluripotent stem cell-enriched human dental pulp-derived cells.

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Patent Owner(s)

Patent OwnerAddress
JCR PHARMACEUTICALS CO LTDASHIYA-SHI HYOGO 659-0021
NIPPON MEDICAL SCHOOL FOUNDATION1-1-5 SENDAGI BUNKYO-KU TOKYO 113-8602
NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY4-1-1 OGAWAHIGASHI-CHO KODAIRA-SHI TOKYO 1878551 ?1878551

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
IMAGAWA, Kiwamu Kobe-shi, Hyogo, JP 8 16
KASAHARA, Yuko Kodaira-shi, Tokyo, JP 6 0
OKADA, Takashi Bunkyo-ku, Tokyo, JP 461 5155

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