GENOTYPE- OR PHENOTYPE-BASED DRUG FORMULATION
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United States of America Patent
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Issued Date -
Nov 16, 2017
app pub date -
Jun 16, 2017
filing date -
Jun 1, 2012
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Abstract
The invention relates to a combination of two or more pharmaceutically active substances, of which at least one is a metabolic product (“metabolite”) of the other (“parent substance”), wherein in particular the dosages thereof are selected such that genotypically or phenotypically related variability in the conversion of the parent substance to the metabolite in particular individuals is compensated for.
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