PANICEIN COMPOUNDS, COMPOSITIONS AND USES THEREOF

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United States of America Patent

SERIAL NO

15522300

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to the fields of medicine and cancer treatment. The invention more specifically relates to the use of a panicein or a derivative thereof, to decrease or inhibit, in vitro or ex vivo, the Patched receptor drug efflux activity, in particular the chemotherapeutic drug efflux activity and chemotherapy resistance. The present disclosure further relates to uses of such compounds, in particular to prepare a pharmaceutical composition to allow or improve the efficiency of a therapy of cancer in a subject in need thereof. The compound of the invention can indeed be advantageously used, in combination with at least one chemotherapeutic drug, for treating cancer, for preventing cancer metastasis and/or for preventing cancer recurrence in a subject. The invention also discloses methods for preventing or treating cancer, cancer metastasis and/or cancer recurrence in a subject, as well as kits suitable for preparing a composition according to the present invention and/or for implementing the herein described methods.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITE NICE SOPHIA ANTIPOLIS28 AVENUE VALROSE NICE F-06103

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AZOULAY, STÉPHANE NICE, FR 2 0
MUS-VETEAU, ISABELLE GRASSE, FR 3 1
THOMAS, OLIVIER GALWAY, IE 39 1215
TRIBALAT, MARIE-AUDE LES ARCS, FR 2 0

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